
翟倩倩,女,1984年7月生人,于2013年7月獲北京協(xié)和醫(yī)學(xué)院微生物與生化藥學(xué)專業(yè)博士學(xué)位,現(xiàn)任中國(guó)水產(chǎn)科學(xué)研究院黃海水產(chǎn)研究所副研究員,碩士生導(dǎo)師。主要從事水產(chǎn)藥理學(xué)及健康養(yǎng)殖等方面的研究,主持國(guó)家自然科學(xué)基金、山東省自然科學(xué)基金、中國(guó)水產(chǎn)科學(xué)研究院基本科研業(yè)務(wù)費(fèi)重點(diǎn)項(xiàng)目等科研項(xiàng)目6項(xiàng),作為骨干參與國(guó)家現(xiàn)代農(nóng)業(yè)產(chǎn)業(yè)技術(shù)體系、國(guó)家自然科學(xué)基金面上項(xiàng)目、國(guó)家重點(diǎn)研發(fā)計(jì)劃子課題等項(xiàng)目10余項(xiàng);發(fā)表研究論文28篇(SCI收錄20篇)、以第一發(fā)明人授權(quán)國(guó)家發(fā)明專利4項(xiàng)、參編專著2部、研究成果獲中國(guó)水產(chǎn)學(xué)會(huì)范蠡科學(xué)技術(shù)獎(jiǎng)一等獎(jiǎng)(2019,16/20)、中國(guó)水產(chǎn)科學(xué)研究院科學(xué)技術(shù)獎(jiǎng)二等獎(jiǎng),2021,12/15);2022年入選中國(guó)水產(chǎn)科學(xué)研究院“水科英才”培育計(jì)劃拔尖人才。
聯(lián)系電話,0532-85826690
通訊地址:山東省青島市南京路106號(hào)中國(guó)水產(chǎn)科學(xué)研究院黃海水產(chǎn)研究所
郵政編碼:266071
E-mail:zhaiqq@www.energicube.com
主要研究?jī)?nèi)容、研究方向
主要進(jìn)行水產(chǎn)病原菌耐藥性、水產(chǎn)藥物代謝動(dòng)力學(xué)、藥效學(xué)評(píng)價(jià)和藥物安全使用技術(shù)等研究,在水產(chǎn)病原菌耐藥性評(píng)估及耐藥機(jī)制研究、中西藥聯(lián)用藥效和安全性評(píng)價(jià)、海水養(yǎng)殖動(dòng)物ABC轉(zhuǎn)運(yùn)蛋白的功能和調(diào)控機(jī)制、常用水產(chǎn)藥物代謝動(dòng)力學(xué)、水產(chǎn)動(dòng)物生理藥動(dòng)學(xué)模型等方面開展了深入研究。
研究方向:1)水產(chǎn)病原菌耐藥性研究;2)水產(chǎn)藥物藥效學(xué);3)水產(chǎn)藥物代謝動(dòng)力學(xué)及藥物殘留預(yù)測(cè)。
代表性論著(10篇以內(nèi))
1. Zhai QQ, Chang ZQ, Li JT, Li J. Effects of combined florfenicol and chlorogenic acid to treat acute hepatopancreatic necrosis disease in Litopenaeus vannamei caused by Vibrio parahaemolyticus. Aquaculture, 2022, 547: 737462.
2. Zhai QQ, Chang ZQ, Li JT, Li J. Protective Effects of Combined Utilization of Quercetin and Florfenicol on Acute Hepatopancreatic Necrosis Syndrome Infected Litopenaeus vannamei. Antibiotics, 2022, 11(12): 1784.
3. Zhai QQ, Xu Y, Li CP, Feng YY, Cui YT, Ma L, Li J. Inhibition of breast cancer resistance protein (BCRP) by Ko143 can affect pharmacokinetics of enrofloxacin in Exopalaemon carinicauda. Journal of Ocean University of China, 2020, 19(5): 1116-1124.
4. Zhai QQ, Li J. Effectiveness of traditional Chinese herbal medicine, San-Huang-San, in combination with enrofloxacin to treat AHPND-causing strain of Vibrio parahaemolyticus in fection in Litopenaeus vannamei. Fish and Shellfish Immunology, 2019, 87: 360-370.
5. Zhai QQ, Li J, Feng YY, Ge QQ. Evaluation of combination effects of Astragalus polysaccharides and florfenicol against acute hepatopancreatic necrosis disease-causing strain of Vibrio parahaemolyticus in Litopenaeus vannamei. Fish and Shellfish Immunology, 2019, 86: 374-383.
6. Zhai QQ, Li J, Chang ZQ. cDNA cloning, characterization and expression analysis of ATP-binding cassette transmembrane transporter in Exopalaemon carinicauda. Aquaculture Research, 2017, 48(8): 4143-4154.
7. Zhai QQ, Pang J, Li GQ, et al. Preclinical pharmacokinetic analysis of (E)-Methyl-4-aryl-4-oxabut-2-enoate, a novel SerThr protein kinase PknB inhibitor, in rats. Acta Poloniae Pharmaceutica. 2017, 74(1): 299-307.
8. Zhai QQ, Pang J, Li GQ, et al. 2015-Validated LC-MS/MS method for determination of YH-8, a novel PKnB inhibitor, in rat plasma and its application to pharmacokinetic study. Acta Pharmaceutica Sinica B. 2015, 5(5): 467-472.
9. Feng YY, Zhai QQ, Wang JJ, Li JT, Li J. Comparison of florfenicol pharmacokinetics in Exopalaemon carinicauda at different temperatures and administration routes. 2019, 42: 230-238.
10.翟倩倩,李健. 恩諾沙星對(duì)脊尾白蝦APND、ECOD和GST活性的影響. 海洋科學(xué). 2017, 41(2): 53-60.